7VJT
Crystal Structure of Mtb Pks13-TE in complex with inhibitor coumestan derivative 8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Polyketide synthase Pks13 (Termination polyketide synthase) | polymer | 291 | 32165.1 | 2 | UniProt (A0A654TNE3) Pfam (PF00975) UniProt (by SIFTS) (I6X8D2) | Mycobacterium tuberculosis | |
| 2 | C, D (A, B) | 3,8-bis(oxidanyl)-7-(piperidin-1-ylmethyl)-[1]benzofuro[3,2-c]chromen-6-one | non-polymer | 365.4 | 2 | Chemie (7IJ) PubChem (155545329) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A, B: 1451 - 1733 (UniProt: A0A654TNE3)
| PDB | External Database | Details |
|---|---|---|
| Ser 1443 | - | expression tag |
| Asn 1444 | - | expression tag |
| Ile 1445 | - | expression tag |
| Gly 1446 | - | expression tag |
| Ser 1447 | - | expression tag |
| Gly 1448 | - | expression tag |
| Gly 1449 | - | expression tag |
| Ser 1450 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64330.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 730.8 | |
| All* | Total formula weight | 65061.0 |
