7VJT
Crystal Structure of Mtb Pks13-TE in complex with inhibitor coumestan derivative 8
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Polyketide synthase Pks13 (Termination polyketide synthase) | polymer | 291 | 32165.1 | 2 | UniProt (A0A654TNE3) Pfam (PF00975) UniProt (by SIFTS) (I6X8D2) In PDB | Mycobacterium tuberculosis | |
2 | A, B | 3,8-bis(oxidanyl)-7-(piperidin-1-ylmethyl)-[1]benzofuro[3,2-c]chromen-6-one | non-polymer | 365.4 | 2 | Chemie (7IJ) | |||
3 | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A, B: 1451 - 1733 (UniProt: A0A654TNE3)
PDB | External Database | Details |
---|---|---|
Ser 1443 | - | expression tag |
Asn 1444 | - | expression tag |
Ile 1445 | - | expression tag |
Gly 1446 | - | expression tag |
Ser 1447 | - | expression tag |
Gly 1448 | - | expression tag |
Gly 1449 | - | expression tag |
Ser 1450 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 64330.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 730.8 | |
All* | Total formula weight | 65061.0 |