7VH3

Cryo-EM structure of Machupo virus polymerase L

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA-directed RNA polymerase L	polymer	2238	253456.3	1	UniProt (Q6IUF8) Pfam (PF17296) Pfam (PF06317) In PDB	Machupo virus (MACV)	Protein L,Large structural protein,Replicase,Transcriptase

Sequence modifications

A: 1 - 2209 (UniProt: Q6IUF8)

PDB	External Database	Details
Trp 2210	-	expression tag
Ser 2211	-	expression tag
His 2212	-	expression tag
Pro 2213	-	expression tag
Gln 2214	-	expression tag
Phe 2215	-	expression tag
Glu 2216	-	expression tag
Lys 2217	-	expression tag
Gly 2218	-	expression tag
Gly 2219	-	expression tag
Gly 2220	-	expression tag
Ser 2221	-	expression tag
Gly 2222	-	expression tag
Gly 2223	-	expression tag
Gly 2224	-	expression tag
Ser 2225	-	expression tag
Gly 2226	-	expression tag
Gly 2227	-	expression tag
Ser 2228	-	expression tag
Ser 2229	-	expression tag
Ala 2230	-	expression tag
Trp 2231	-	expression tag
Ser 2232	-	expression tag
His 2233	-	expression tag
Pro 2234	-	expression tag
Gln 2235	-	expression tag
Phe 2236	-	expression tag
Glu 2237	-	expression tag
Lys 2238	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	253456.3
All*	Total formula weight	253456.3

*Water molecules are not included.