7VH0
MT2-remalteon-Gi complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Melatonin receptor type 1B | polymer | 362 | 40308.3 | 1 | UniProt (P49286) Pfam (PF00001) In PDB | Homo sapiens (human) | Mel-1B-R,Mel1b receptor |
2 | B | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40340.9 | 1 | UniProt (P63096) Pfam (PF00503) In PDB | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
3 | C | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 353 | 39021.6 | 1 | UniProt (P54311) Pfam (PF00400) In PDB | Rattus norvegicus (Norway rat) | Transducin beta chain 1 |
4 | D, E | scFv16 | polymer | 323 | 34767.0 | 2 | Homo sapiens (Bovine) | ||
5 | A | N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide | non-polymer | 259.3 | 1 | Chemie (JEV) |
Sequence modifications
A: 1 - 362 (UniProt: P49286)
B: 2 - 354 (UniProt: P63096)
C: 2 - 340 (UniProt: P54311)
PDB | External Database | Details |
---|---|---|
Phe 108 | Leu 108 | conflict |
Trp 129 | Phe 129 | conflict |
Leu 140 | Cys 140 | conflict |
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
Met -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Leu -1 | - | expression tag |
Leu 0 | - | expression tag |
Gln 1 | - | expression tag |
Glu 6 | Gln 6 | conflict |
Gln 130 | Glu 130 | conflict |
Asp 237 | Asn 237 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 189204.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 259.3 | |
All* | Total formula weight | 189464.2 |