7VGZ
MT1-remalteon-Gi complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B | Melatonin receptor type 1A | polymer | 350 | 39408.6 | 1 | UniProt (P48039) Pfam (PF00001) In PDB | Homo sapiens (human) | Mel-1A-R,Mel1a receptor |
| 2 | C | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 353 | 40283.8 | 1 | UniProt (P63096) Pfam (PF00503) In PDB | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 3 | D | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37728.2 | 1 | UniProt (P54311) Pfam (PF00400) In PDB | Rattus norvegicus (Norway rat) | Transducin beta chain 1 |
| 4 | E | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 67 | 7432.6 | 1 | UniProt (P63212) Pfam (PF00631) In PDB | Bos taurus (cattle) | G gamma-I |
| 5 | F | scFv16 | polymer | 256 | 27340.5 | 1 | synthetic construct | ||
| 6 | B | N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide | non-polymer | 259.3 | 1 | Chemie (JEV) | |||
| 7 | B | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence modifications
D: 2 - 340 (UniProt: P54311)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 152193.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 646.0 | |
| All* | Total formula weight | 152839.6 |
