7VGQ
Cryo-EM structure of Machupo virus polymerase L in complex with matrix protein Z
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA-directed RNA polymerase L | polymer | 2238 | 253456.3 | 1 | UniProt (Q6IUF8) Pfam (PF17296) Pfam (PF06317) | Machupo virus (MACV) | Protein L,Large structural protein,Replicase,Transcriptase |
| 2 | B (B) | Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z | polymer | 496 | 54913.9 | 1 | UniProt (P0AEX9) UniProt (Q6IUF9) Pfam (PF01547) Pfam (PF03854) | Escherichia coli (strain K12) | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,Protein Z,Zinc-binding protein |
| 3 | C, D (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 1 - 2209 (UniProt: Q6IUF8)
B: -392 - -27 (UniProt: P0AEX9)
B: 2 - 94 (UniProt: Q6IUF9)
| PDB | External Database | Details |
|---|---|---|
| Trp 2210 | - | expression tag |
| Ser 2211 | - | expression tag |
| His 2212 | - | expression tag |
| Pro 2213 | - | expression tag |
| Gln 2214 | - | expression tag |
| Phe 2215 | - | expression tag |
| Glu 2216 | - | expression tag |
| Lys 2217 | - | expression tag |
| Gly 2218 | - | expression tag |
| Gly 2219 | - | expression tag |
| Gly 2220 | - | expression tag |
| Ser 2221 | - | expression tag |
| Gly 2222 | - | expression tag |
| Gly 2223 | - | expression tag |
| Gly 2224 | - | expression tag |
| Ser 2225 | - | expression tag |
| Gly 2226 | - | expression tag |
| Gly 2227 | - | expression tag |
| Ser 2228 | - | expression tag |
| Ser 2229 | - | expression tag |
| Ala 2230 | - | expression tag |
| Trp 2231 | - | expression tag |
| Ser 2232 | - | expression tag |
| His 2233 | - | expression tag |
| Pro 2234 | - | expression tag |
| Gln 2235 | - | expression tag |
| Phe 2236 | - | expression tag |
| Glu 2237 | - | expression tag |
| Lys 2238 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -401 | - | expression tag |
| His -400 | - | expression tag |
| His -399 | - | expression tag |
| His -398 | - | expression tag |
| His -397 | - | expression tag |
| His -396 | - | expression tag |
| His -395 | - | expression tag |
| His -394 | - | expression tag |
| His -393 | - | expression tag |
| Asn -26 | - | linker |
| Ser -25 | - | linker |
| Ser -24 | - | linker |
| Ser -23 | - | linker |
| Asn -22 | - | linker |
| Asn -21 | - | linker |
| Asn -20 | - | linker |
| Asn -19 | - | linker |
| Asn -18 | - | linker |
| Asn -17 | - | linker |
| Asn -16 | - | linker |
| Asn -15 | - | linker |
| Asn -14 | - | linker |
| Asn -13 | - | linker |
| Leu -12 | - | linker |
| Gly -11 | - | linker |
| Ile -10 | - | linker |
| Glu -9 | - | linker |
| Leu -8 | - | linker |
| Glu -7 | - | linker |
| Val -6 | - | linker |
| Leu -5 | - | linker |
| Phe -4 | - | linker |
| Gln -3 | - | linker |
| Gly -2 | - | linker |
| Pro -1 | - | linker |
| Gly 0 | - | linker |
| Ser 1 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 308370.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 308501.0 |
