7VGF

cryo-EM structure of AMP-PNP bound human ABCB7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Iron-sulfur clusters transporter ABCB7, mitochondrial	polymer	697	76879.9	2	UniProt (O75027) Pfam (PF00664) Pfam (PF00005)	Homo sapiens (human)	ATP-binding cassette sub-family B member 7,mitochondrial,ATP-binding cassette transporter 7,ABC transporter 7 protein
2	C, E (A, B)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
3	D, F (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Sequence modifications

A, B: 72 - 751 (UniProt: O75027)

PDB	External Database	Details
Met 71	-	initiating methionine
Asp 752	-	expression tag
Tyr 753	-	expression tag
Lys 754	-	expression tag
Asp 755	-	expression tag
Asp 756	-	expression tag
Asp 757	-	expression tag
Asp 758	-	expression tag
Lys 759	-	expression tag
Asp 760	-	expression tag
Tyr 761	-	expression tag
Lys 762	-	expression tag
Asp 763	-	expression tag
Asp 764	-	expression tag
Asp 765	-	expression tag
Asp 766	-	expression tag
Lys 767	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	153759.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1061.0
All*	Total formula weight	154820.8

*Water molecules are not included.