7VF3

Plexin B1 extracellular fragment in complex with lasso-grafted PB1m7 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Plexin-B1	polymer	525	56661.4	2	UniProt (O43157) Pfam (PF01403) Pfam (PF01437) In PDB	Homo sapiens (Human)	Semaphorin receptor SEP
2	B, D	Uteroglobin,PB1m7 peptide,Uteroglobin	polymer	155	17477.0	2	UniProt (P11684) Pfam (PF01099) In PDB	Homo sapiens (Human)	Clara cell phospholipid-binding protein,CCPBP,Clara cells 10 kDa secretory protein,CC10,Secretoglobin family 1A member 1,Urinary protein 1,UP-1,UP1,Urine protein 1
3	A, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
5	C	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
6	C	TETRAETHYLENE GLYCOL	non-polymer		194.2	4	Chemie (PG4)
7		water	water		18.0	146	Chemie (HOH)

Sequence modifications

A, C: 19 - 535 (UniProt: O43157)

PDB	External Database	Details
Ser 19	Thr 19	engineered mutation
Thr 536	-	expression tag
Arg 537	-	expression tag
Glu 538	-	expression tag
Asn 539	-	expression tag
Leu 540	-	expression tag
Tyr 541	-	expression tag
Phe 542	-	expression tag
Gln 543	-	expression tag

B, D: 29 - 97 (UniProt: P11684)

PDB	External Database	Details
Ser 29	Ala 21	engineered mutation

B, D: 98 - 116 (PDB: 7VF3)
B, D: 117 - 183 (UniProt: P11684)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	148276.8
Non-Polymers*	Number of molecules	8
	Total formula weight	1475.6
All*	Total formula weight	149752.4

*Water molecules are not included.