7VD4
Crystal structure of BPTF-BRD with ligand TP248 bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Nucleosome-remodeling factor subunit BPTF | polymer | 114 | 13386.3 | 1 | UniProt (J3QQQ8) Pfam (PF00439) UniProt (by SIFTS) (Q12830) In PDB | Homo sapiens (Human) | |
| 2 | A | 6-[4-[3-(dimethylamino)propoxy]phenyl]-N-methyl-2-methylsulfonyl-pyrimidin-4-amine | non-polymer | 364.5 | 1 | Chemie (6FI) | |||
| 3 | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A: 65 - 174 (UniProt: J3QQQ8)
| PDB | External Database | Details |
|---|---|---|
| Pro 61 | - | expression tag |
| Leu 62 | - | expression tag |
| Gly 63 | - | expression tag |
| Ser 64 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13386.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 364.5 | |
| All* | Total formula weight | 13750.7 |
