7VC3
Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L97 and L-proline at 1.97 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Prolyl-tRNA synthetase (ProRS) | polymer | 500 | 57937.3 | 1 | UniProt (A0A7J6JUK2) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) In PDB | Toxoplasma gondii | |
| 2 | A | 4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide | non-polymer | 477.5 | 1 | Chemie (1XK) | |||
| 3 | A | PROLINE | non-polymer | 115.1 | 1 | Chemie (PRO) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | A | CHLORIDE ION | non-polymer | 35.5 | 11 | Chemie (CL) | |||
| 6 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | A | SULFITE ION | non-polymer | 80.1 | 1 | Chemie (SO3) | |||
| 8 | A | ETHANOLAMINE | non-polymer | 61.1 | 1 | Chemie (ETA) | |||
| 9 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A: 334 - 830 (UniProt: A0A7J6JUK2)
| PDB | External Database | Details |
|---|---|---|
| Gly 331 | - | expression tag |
| Ala 332 | - | expression tag |
| Met 333 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57937.3 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1423.1 | |
| All* | Total formula weight | 59360.3 |
