7VBB
Structure of the post state human RNA Polymerase I Elongation Complex
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA-directed RNA polymerase I subunit RPA1 | polymer | 1719 | 194911.9 | 1 | UniProt (O95602) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB | Homo sapiens (Human) | RNA polymerase I subunit A1,A190,DNA-directed RNA polymerase I largest subunit,DNA-directed RNA polymerase I subunit A,RNA polymerase I 194 kDa subunit,RPA194 |
2 | B | DNA-directed RNA polymerase I subunit RPA2 | polymer | 1135 | 128379.2 | 1 | UniProt (Q9H9Y6) Pfam (PF00562) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF06883) In PDB | Homo sapiens (Human) | RNA polymerase I subunit 2,DNA-directed RNA polymerase I 135 kDa polypeptide,RPA135 |
3 | C | DNA-directed RNA polymerases I and III subunit RPAC1 | polymer | 346 | 39301.7 | 1 | UniProt (O15160) Pfam (PF01193) Pfam (PF01000) In PDB | Homo sapiens (Human) | RNA polymerases I and III subunit AC1,AC40,DNA-directed RNA polymerases I and III 40 kDa polypeptide,RPA40,RPA39,RPC40 |
4 | E | DNA-directed RNA polymerases I, II, and III subunit RPABC1 | polymer | 210 | 24584.2 | 1 | UniProt (P19388) Pfam (PF03871) Pfam (PF01191) In PDB | Homo sapiens (Human) | RNA polymerases I,II,and III subunit ABC1,DNA-directed RNA polymerase II 23 kDa polypeptide,DNA-directed RNA polymerase II subunit E,RPB5 homolog,XAP4 |
5 | F | DNA-directed RNA polymerases I, II, and III subunit RPABC2 | polymer | 127 | 14491.0 | 1 | UniProt (P61218) Pfam (PF01192) In PDB | Homo sapiens (Human) | RNA polymerases I,II,and III subunit ABC2,DNA-directed RNA polymerase II subunit F,DNA-directed RNA polymerases I,and III 14.4 kDa polypeptide,RPABC14.4,RPB14.4,RPB6 homolog,RPC15 |
6 | H | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 150 | 17162.3 | 1 | UniProt (P52434) Pfam (PF03870) In PDB | Homo sapiens (Human) | RNA polymerases I,II,and III subunit ABC3,DNA-directed RNA polymerase II subunit H,DNA-directed RNA polymerases I,and III 17.1 kDa polypeptide,RPB17,RPB8 homolog,hRPB8 |
7 | I | DNA-directed RNA polymerase I subunit RPA12 | polymer | 126 | 13917.7 | 1 | UniProt (Q9P1U0) Pfam (PF01096) In PDB | Homo sapiens (Human) | DNA-directed RNA polymerase I subunit H,Zinc ribbon domain-containing protein 1 |
8 | J | DNA-directed RNA polymerases I, II, and III subunit RPABC5 | polymer | 67 | 7655.1 | 1 | UniProt (P62875) Pfam (PF01194) In PDB | Homo sapiens (Human) | RNA polymerases I,II,and III subunit ABC5,DNA-directed RNA polymerase III subunit L,RNA polymerase II 7.6 kDa subunit,RPB7.6,RPB10 homolog |
9 | K | DNA-directed RNA polymerases I and III subunit RPAC2 | polymer | 133 | 15259.2 | 1 | UniProt (P0DPB6) Pfam (PF13656) In PDB | Homo sapiens (Human) | RNA polymerases I and III subunit AC2,AC19,DNA-directed RNA polymerase I subunit D,RNA polymerase I 16 kDa subunit,RPA16,RPC16,hRPA19 |
10 | L | DNA-directed RNA polymerases I, II, and III subunit RPABC4 | polymer | 58 | 7018.2 | 1 | UniProt (P53803) Pfam (PF03604) In PDB | Homo sapiens (Human) | RNA polymerases I,II,and III subunit ABC4,ABC10-alpha,DNA-directed RNA polymerase II subunit K,RNA polymerase II 7.0 kDa subunit,RPB7.0,RPB10alpha |
11 | N | DNA-directed RNA polymerase I subunit RPA34 | polymer | 510 | 55065.5 | 1 | UniProt (O15446) Pfam (PF08208) In PDB | Homo sapiens (Human) | A34.5,Antisense to ERCC-1 protein,ASE-1,CD3-epsilon-associated protein,CD3E-associated protein,DNA-directed RNA polymerase I subunit G,RNA polymerase I-associated factor PAF49 |
12 | G | DNA-directed RNA polymerase I subunit RPA43 | polymer | 338 | 37490.4 | 1 | UniProt (Q3B726) Pfam (PF03876) Pfam (PF17875) In PDB | Homo sapiens (Human) | DNA-directed RNA polymerase I subunit F,Twist neighbor protein |
13 | M | DNA-directed RNA polymerase I subunit RPA49 | polymer | 419 | 47330.2 | 1 | UniProt (Q9GZS1) Pfam (PF06870) In PDB | Homo sapiens (Human) | RNA polymerase I subunit A49,DNA-directed RNA polymerase I subunit E,RNA polymerase I-associated factor 1,RNA polymerase I-associated factor 53 |
14 | R | RNA (5'-R(P*UP*GP*CP*UP*GP*AP*CP*U)-3') | polymer | 8 | 2503.5 | 1 | Homo sapiens (Human) | ||
15 | T | DNA (25-MER) | polymer | 25 | 7727.0 | 1 | Homo sapiens (Human) | ||
16 | U | DNA (5'-D(*CP*TP*GP*TP*CP*CP*TP*CP*TP*GP*GP*CP*GP*A)-3') | polymer | 14 | 4247.8 | 1 | Homo sapiens (Human) | ||
17 | A, B, J, L | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
18 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 16 |
Total formula weight | 617045.0 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 351.4 | |
All* | Total formula weight | 617396.3 |