7VA1
Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with GDD-04-35
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A, C, D | D-3-phosphoglycerate dehydrogenase | polymer | 214 | 22961.4 | 4 | UniProt (O43175) Pfam (PF00389) Pfam (PF02826) In PDB | Homo sapiens (Human) | 3-PGDH,2-oxoglutarate reductase,Malate dehydrogenase |
| 2 | B, A, C, D | 4-[(3-ethanoylphenyl)sulfamoyl]-~{N}-[4-(3-fluorophenyl)-1,3-thiazol-2-yl]benzamide | non-polymer | 495.5 | 4 | Chemie (5YP) | |||
| 3 | water | water | 18.0 | 382 | Chemie (HOH) |
Sequence modifications
B, A, C, D: 96 - 307 (UniProt: O43175)
| PDB | External Database | Details |
|---|---|---|
| Gly 94 | - | expression tag |
| Ser 95 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 91845.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1982.2 | |
| All* | Total formula weight | 93827.7 |
