7V7L
Crystal Structure of the Heterodimeric HIF-3a:ARNT Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Aryl hydrocarbon receptor nuclear translocator | polymer | 359 | 40683.1 | 1 | UniProt (P53762) Pfam (PF00010) Pfam (PF00989) Pfam (PF14598) In PDB | Mus musculus (Mouse) | ARNT protein |
| 2 | B | Hypoxia-inducible factor 3-alpha | polymer | 364 | 40701.2 | 1 | UniProt (Q0VBL6) Pfam (PF00989) Pfam (PF14598) In PDB | Mus musculus (Mouse) | HIF-3-alpha,HIF3-alpha |
| 3 | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence modifications
A: 82 - 464 (UniProt: P53762)
B: 4 - 358 (UniProt: Q0VBL6)
| PDB | External Database | Details |
|---|---|---|
| Met 81 | - | initiating methionine |
| - | Leu 232 | deletion |
| - | Thr 233 | deletion |
| - | Gly 234 | deletion |
| - | Arg 235 | deletion |
| - | Val 236 | deletion |
| - | Leu 237 | deletion |
| - | Asp 238 | deletion |
| - | Leu 239 | deletion |
| - | Lys 240 | deletion |
| - | Thr 241 | deletion |
| - | Gly 242 | deletion |
| - | Thr 243 | deletion |
| - | Val 244 | deletion |
| - | Lys 245 | deletion |
| - | Lys 246 | deletion |
| - | Glu 247 | deletion |
| - | Gly 248 | deletion |
| - | Gln 249 | deletion |
| - | Gln 250 | deletion |
| - | Ser 251 | deletion |
| - | Ser 252 | deletion |
| - | Met 253 | deletion |
| - | Arg 254 | deletion |
| - | Met 255 | deletion |
| - | Cys 256 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| Leu 359 | - | expression tag |
| Glu 360 | - | expression tag |
| His 361 | - | expression tag |
| His 362 | - | expression tag |
| His 363 | - | expression tag |
| His 364 | - | expression tag |
| His 365 | - | expression tag |
| His 366 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 81384.3 | |
| All* | Total formula weight | 81384.3 |
