7V6Z
Cryo-EM structure of Patched1 (V1084A mutant) in lipid nanodisc, 3.64 angstrom (reprocessed with the dataset of 7dzp)
Replaces: 7DZPEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Protein patched homolog 1,Protein patched homolog 1 | polymer | 1090 | 121609.6 | 1 | UniProt (Q61115) Pfam (PF12349) Pfam (PF02460) In PDB | Mus musculus (Mouse) | PTC,PTC1,PTC,PTC1 |
| 2 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 4 | A | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence modifications
A: 2 - 709 (UniProt: Q61115)
A: 710 - 1175 (UniProt: Q61115)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 1084 | Val 1084 | engineered mutation |
| Thr 1176 | - | expression tag |
| Leu 1177 | - | expression tag |
| Glu 1178 | - | expression tag |
| Val 1179 | - | expression tag |
| Leu 1180 | - | expression tag |
| Phe 1181 | - | expression tag |
| Gln 1182 | - | expression tag |
| Gly 1183 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 121609.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1050.3 | |
| All* | Total formula weight | 123084.2 |
