7V6Q

Crystal structure of sNASP-ASF1A-H3.1-H4 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Histone chaperone ASF1A	polymer	156	17799.9	2	UniProt (Q9Y294) Pfam (PF04729) In PDB	Homo sapiens (Human)	Anti-silencing function protein 1 homolog A,hAsf1,hAsf1a,CCG1-interacting factor A,CIA,hCIA
2	B, F	Histone H3.1	polymer	136	15437.2	2	UniProt (P68431) Pfam (PF00125) In PDB	Homo sapiens (Human)
3	C, G	Histone H4	polymer	102	11307.3	2	UniProt (P62805) Pfam (PF15511) In PDB	Homo sapiens (Human)
4	D, H	Isoform 2 of Nuclear autoantigenic sperm protein	polymer	283	31924.9	2	UniProt (P49321) Pfam (PF10516) In PDB	Homo sapiens (Human)	NASP
5	A, B, C, E, F	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
6	C, G	PENTAETHYLENE GLYCOL	non-polymer		238.3	2	Chemie (1PE)
7		water	water		18.0	44	Chemie (HOH)

Sequence modifications

C, G: 2 - 102 (UniProt: P62805)

PDB	External Database	Details
Met 1	-	initiating methionine

D, H: 38 - 320 (UniProt: P49321)

PDB	External Database	Details
Pro 39	Val 39	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	152938.6
Non-Polymers*	Number of molecules	8
	Total formula weight	1029.1
All*	Total formula weight	153967.7

*Water molecules are not included.