7V3Z
Structure of cannabinoid receptor type 1(CB1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | fusion protein of Cannabinoid receptor 1 and Flavodoxin | polymer | 438 | 48602.6 | 1 | UniProt (P21554) UniProt (P00323) Pfam (PF00001) Pfam (PF00258) In PDB | Homo sapiens (Human) | CB-R,CB1,CANN6 |
| 2 | A | 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol | non-polymer | 376.6 | 1 | Chemie (9GF) | |||
| 3 | A | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) | |||
| 4 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) |
Sequence modifications
A: 102 - 306 (UniProt: P21554)
A: 308 - 453 (UniProt: P00323)
A: 458 - 536 (UniProt: P21554)
| PDB | External Database | Details |
|---|---|---|
| Gly 99 | - | expression tag |
| Glu 100 | - | expression tag |
| Asn 101 | - | expression tag |
| Leu 154 | His 154 | engineered mutation |
| Ala 210 | Thr 210 | engineered mutation |
| Lys 273 | Glu 273 | engineered mutation |
| Val 283 | Thr 283 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Trp 403 | Tyr 98 | engineered mutation |
| Pro | - | linker |
| Asp | - | linker |
| Gln | - | linker |
| Ala | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 307 | - | linker |
| Glu 462 | Arg 340 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 48602.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1219.6 | |
| All* | Total formula weight | 49822.2 |
