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7V3P

Cryo-EM structure of the IGF1R/insulin complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BInsulin-like growth factor 1 receptorpolymer931105824.72UniProt (P08069)
Pfam (PF01030)
Pfam (PF00757)
In PDB
Homo sapiens (Human)Insulin-like growth factor I receptor,IGF-I receptor
2EInsulin A chainpolymer212383.71UniProt (P01308)
In PDB
Homo sapiens (Human)Small chain
3FInsulin B chainpolymer303434.01UniProt (P01308)
Pfam (PF00049)
In PDB
Homo sapiens (Human)Large chain
4A, B2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight217467.1
Non-Polymers*Number of molecules4
Total formula weight884.8
All*Total formula weight218351.9
*Water molecules are not included.

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PDB entries from 2024-07-24

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