7V3P
Cryo-EM structure of the IGF1R/insulin complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Insulin-like growth factor 1 receptor | polymer | 931 | 105824.7 | 2 | UniProt (P08069) Pfam (PF01030) Pfam (PF00757) | Homo sapiens (Human) | Insulin-like growth factor I receptor,IGF-I receptor |
| 2 | C (E) | Insulin A chain | polymer | 21 | 2383.7 | 1 | UniProt (P01308) | Homo sapiens (Human) | Small chain |
| 3 | D (F) | Insulin B chain | polymer | 30 | 3434.0 | 1 | UniProt (P01308) Pfam (PF00049) | Homo sapiens (Human) | Large chain |
| 4 | E, F, G, H (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 217467.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 218351.9 |
