7V32
Deactive state complex I from rotenone dataset
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | polymer | 431 | 47265.9 | 1 | UniProt (F1RVN1) Pfam (PF01512) Pfam (PF22461) Pfam (PF10589) UniProt (by SIFTS) (A0A4X1SZP7) | Sus scrofa (pig) | |
| 2 | B (B) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | polymer | 176 | 20208.0 | 1 | UniProt (A0A287BDC0) Pfam (PF12838) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 23 kDa subunit,Complex I-23kD |
| 3 | C (C) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7,mitochondrial | polymer | 156 | 17875.0 | 1 | UniProt (I3LK43) Pfam (PF01058) UniProt (by SIFTS) (A0A8D1TL60) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 20 kDa subunit,Complex I-20kD |
| 4 | D (E) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | polymer | 115 | 13813.0 | 1 | UniProt (A0A480VKQ8) Pfam (PF05347) UniProt (by SIFTS) (F1SJP6) | Sus scrofa (pig) | |
| 5 | E (F) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | polymer | 86 | 9841.3 | 1 | UniProt (F1RGE3) Pfam (PF05047) | Sus scrofa (pig) | |
| 6 | F, V (G, X) | Acyl carrier protein, mitochondrial | polymer | 88 | 10133.6 | 2 | UniProt (D0G781) Pfam (PF00550) UniProt (by SIFTS) (A0A287AAR5) | Sus scrofa (pig) | |
| 7 | G (H) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | polymer | 112 | 12949.1 | 1 | UniProt (A0A5G2RN85) | Sus scrofa (pig) | Complex I-13kD-B,NADH-ubiquinone oxidoreductase 13 kDa-B subunit,Complex I subunit B13 |
| 8 | H (I) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | polymer | 112 | 12517.4 | 1 | UniProt (A0A4X1VLA2) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase subunit B14.5a,Complex I-B14.5a |
| 9 | I (J) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | polymer | 341 | 38840.9 | 1 | UniProt (A0A480QJC4) Pfam (PF01370) UniProt (by SIFTS) (A0A287AE88) | Sus scrofa (pig) | |
| 10 | J (K) | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | polymer | 42 | 5046.5 | 1 | UniProt (A0A4X1TFI3) Pfam (PF15880) UniProt (by SIFTS) (I3LRR4) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 9 kDa subunit,Complex I-9kD |
| 11 | K (L) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | polymer | 125 | 14442.4 | 1 | UniProt (G8IFA6) Pfam (PF04800) UniProt (by SIFTS) (A0A4X1SN37) | Sus scrofa (pig) | Complex I-18 kDa,NADH-ubiquinone oxidoreductase 18 kDa subunit |
| 12 | L (M) | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | polymer | 690 | 75770.8 | 1 | UniProt (F1SHD7) Pfam (PF13510) Pfam (PF10588) Pfam (PF22117) Pfam (PF22151) Pfam (PF00384) Pfam (PF09326) UniProt (by SIFTS) (A0A4X1V1H9) | Sus scrofa (pig) | |
| 13 | M (N) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | polymer | 144 | 17031.2 | 1 | UniProt (F1SQP4) Pfam (PF05071) | Sus scrofa (pig) | |
| 14 | N (O) | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | polymer | 217 | 23826.3 | 1 | UniProt (A0A287BG40) Pfam (PF01257) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 24 kDa subunit |
| 15 | O (P) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | polymer | 208 | 24521.7 | 1 | UniProt (A0A286ZNN4) Pfam (PF00329) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 30 kDa subunit,Complex I-30kD |
| 16 | P (Q) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | polymer | 430 | 49234.3 | 1 | UniProt (A0A480JYS1) Pfam (PF00346) UniProt (by SIFTS) (F1S1A8) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 49 kDa subunit,Complex I-49kD |
| 17 | Q (S) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 70 | 8088.4 | 1 | UniProt (K7GR43) Pfam (PF15879) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase MWFE subunit,Complex I-MWFE |
| 18 | R (T) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | polymer | 96 | 10567.6 | 1 | UniProt (F1S031) Pfam (PF10276) | Sus scrofa (pig) | |
| 19 | S (U) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 | polymer | 83 | 9094.4 | 1 | UniProt (A0A4X1VQ42) Pfam (PF14987) UniProt (by SIFTS) (A0A4X1VPG4) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B9 subunit,Complex I-B9 |
| 20 | T (V) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | polymer | 140 | 14555.7 | 1 | UniProt (I3LGM4) Pfam (PF02466) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase subunit B14.7,Complex I-B14.7 |
| 21 | U (W) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | polymer | 142 | 16709.3 | 1 | UniProt (F1S6Q1) Pfam (PF06212) UniProt (by SIFTS) (A0A8D1NRT6) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B16.6 subunit,Complex I-B16.6 |
| 22 | W (Y) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial | polymer | 70 | 8430.3 | 1 | UniProt (A0A4X1V766) Pfam (PF14813) UniProt (by SIFTS) (A0A5G2QW32) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase AGGG subunit,Complex I-AGGG |
| 23 | X (Z) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | polymer | 84 | 9504.7 | 1 | UniProt (A0A287AS93) Pfam (PF08122) UniProt (by SIFTS) (A0A4X1VD84) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B12 subunit,Complex I-B12 |
| 24 | Y (a) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | polymer | 140 | 16477.1 | 1 | UniProt (F1SGC6) Pfam (PF09781) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase SGDH subunit,Complex I-SGDH |
| 25 | Z (b) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | polymer | 126 | 15333.8 | 1 | UniProt (Q2EN80) Pfam (PF09782) UniProt (by SIFTS) (A0A480KM09) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B17 subunit,Complex I-B17 |
| 26 | AA (c) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | polymer | 156 | 18608.8 | 1 | UniProt (F1RWL7) Pfam (PF05821) | Sus scrofa (pig) | Complex I-ASHI,NADH-ubiquinone oxidoreductase ASHI subunit |
| 27 | BA (d) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | polymer | 175 | 20813.6 | 1 | UniProt (A0A4X1VYV0) Pfam (PF10249) UniProt (by SIFTS) (I3LDC3) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase PDSW subunit,Complex I-PDSW |
| 28 | CA (e) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | polymer | 107 | 12635.1 | 1 | Pfam (PF10183) UniProt (by SIFTS) (A0A287BMW6) | Sus scrofa (pig) | |
| 29 | DA (f) | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial | polymer | 42 | 4945.7 | 1 | UniProt (A1XQS6) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase KFYI subunit,Complex I-KFYI |
| 30 | EA (g) | NADH dehydrogenase [ubiquinone] 1 subunit C2 | polymer | 121 | 14196.5 | 1 | UniProt (A0A480JRW3) Pfam (PF06374) | Sus scrofa (pig) | |
| 31 | FA (h) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | polymer | 105 | 12375.4 | 1 | UniProt (F1SV23) Pfam (PF10200) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 15 kDa subunit,Complex I-15 kDa |
| 32 | GA (i) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 347 | 39077.5 | 1 | UniProt (O79875) Pfam (PF00361) Pfam (PF06444) | Sus scrofa (pig) | NADH dehydrogenase subunit 2 |
| 33 | HA (j) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 113 | 12798.3 | 1 | UniProt (O79880) Pfam (PF00507) | Sus scrofa (pig) | NADH dehydrogenase subunit 3 |
| 34 | IA (k) | NADH-ubiquinone oxidoreductase chain 4L | polymer | 98 | 10827.3 | 1 | UniProt (P56632) Pfam (PF00420) | Sus scrofa (pig) | NADH dehydrogenase subunit 4L |
| 35 | JA (l) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 603 | 68267.0 | 1 | UniProt (Q71K68) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) UniProt (by SIFTS) (Q9TDR1) | Sus scrofa (pig) | |
| 36 | KA (m) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 175 | 19021.3 | 1 | UniProt (O79882) Pfam (PF00499) | Sus scrofa (pig) | NADH dehydrogenase subunit 6 |
| 37 | LA (n) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | polymer | 56 | 6781.9 | 1 | UniProt (F1SD73) Pfam (PF08040) UniProt (by SIFTS) (A0A8D2CGH8) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase MNLL subunit,Complex I-MNLL |
| 38 | MA (o) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | polymer | 128 | 14986.2 | 1 | UniProt (A0A4X1T6M0) Pfam (PF07225) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B15 subunit,Complex I-B15 |
| 39 | NA (p) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | polymer | 178 | 21733.7 | 1 | UniProt (A0A4X1T0A8) Pfam (PF05347) UniProt (by SIFTS) (K7GSE5) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B22 subunit,Complex I-B22 |
| 40 | OA (r) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 459 | 51853.4 | 1 | UniProt (Q7IIB7) Pfam (PF01059) Pfam (PF00361) UniProt (by SIFTS) (O79881) | Sus scrofa (pig) | |
| 41 | PA (s) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 318 | 35667.5 | 1 | UniProt (O79874) Pfam (PF00146) | Sus scrofa (pig) | NADH dehydrogenase subunit 1 |
| 42 | QA (u) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | polymer | 171 | 19932.9 | 1 | UniProt (F1SLR1) Pfam (PF06747) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase 19 kDa subunit,Complex I-19kD |
| 43 | RA (v) | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | polymer | 131 | 15954.3 | 1 | UniProt (F1SCH1) Pfam (PF05676) | Sus scrofa (pig) | NADH-ubiquinone oxidoreductase B18 subunit,Complex I-B18 |
| 44 | SA (w) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | polymer | 320 | 36792.7 | 1 | UniProt (F1SIS9) Pfam (PF01712) | Sus scrofa (pig) | |
| 45 | CB, DB, TA, VA, WA... (M, A, B, C) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 6 | Chemie (SF4) | |||
| 46 | UA (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) PubChem (710) PubChem (8965) PubChem (23585816) PubChem (643976) PubChem (51435500) PubChem (51435503) PubChem (5702760) PubChem (7048779) PubChem (7048781) PubChem (15559251) | |||
| 47 | JB, QB, RB, VB, WB... (U, i, j, l, B...) | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 8 | Chemie (PEE) PubChem (108229) PubChem (44891344) PubChem (54095275) PubChem (14238554) PubChem (6437392) PubChem (9546744) PubChem (99655478) PubChem (99655479) PubChem (5909904) PubChem (9546757) PubChem (138113035) PubChem (171729549) | |||
| 48 | AC, BC, MB, NB, SB... (r, a, g, j, C) | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL | non-polymer | 767.1 | 6 | Chemie (PLX) PubChem (49867511) | |||
| 49 | AB, KB (G, X) | S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate | non-polymer | 540.7 | 2 | Chemie (8Q1) PubChem (119058169) PubChem (122362359) PubChem (162826280) | |||
| 50 | BB (J) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 51 | EB, HB (M, O) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 52 | FB (M) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 53 | GB, LB, OB, PB, TB... (N, a, g, i, l...) | CARDIOLIPIN | non-polymer | 1464.0 | 7 | Chemie (CDL) PubChem (17753886) PubChem (5287898) | |||
| 54 | IB (T) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 55 | CC (s) | Coenzyme Q10, (2Z,6E,10Z,14E,18E,22E,26Z)-isomer | non-polymer | 863.3 | 1 | Chemie (UQ) PubChem (17572160) PubChem (45266508) PubChem (5281915) PubChem (5926222) PubChem (1156) PubChem (6857782) PubChem (9811994) PubChem (12303768) PubChem (12303769) PubChem (97038292) PubChem (97038293) PubChem (5366029) PubChem (5354031) PubChem (6473741) PubChem (124919119) PubChem (124919120) PubChem (131954658) PubChem (137350098) | |||
| 56 | DC (w) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
v: 2 - 131 (UniProt: F1SCH1)
| PDB | External Database | Details |
|---|---|---|
| Myr 1 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 45 |
| Total formula weight | 949481.1 | |
| Non-Polymers* | Number of molecules | 37 |
| Total formula weight | 26928.2 | |
| All* | Total formula weight | 976409.3 |
