7V1H

Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM and m7GTP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Core protein	polymer	265	29948.4	1	UniProt (C4TPE0) Pfam (PF01728) In PDB	Omsk hemorrhagic fever virus (OHFV)	Envelope protein E,Flavivirin protease NS2B regulatory subunit,Flavivirin protease NS3 catalytic subunit,Genome polyprotein,Matrix protein,Non-structural protein 1,Non-structural protein 2A,Non-structural protein 2B,Non-structural protein 3,Non-structural protein 4A,Non-structural protein 4B,Peptide 2k,Peptide pr,Protein prM,RNA-directed RNA polymerase NS5,Serine protease NS3,Serine protease subunit NS2B,Small envelope protein M
2	A	7-METHYL-GUANOSINE-5'-TRIPHOSPHATE	non-polymer		538.2	1	Chemie (MGP)
3	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	A	CITRIC ACID	non-polymer		192.1	1	Chemie (CIT)
5	A	S-ADENOSYLMETHIONINE	non-polymer		398.4	1	Chemie (SAM)
6	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
7	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
8		water	water		18.0	205	Chemie (HOH)

Sequence modifications

A: 7 - 264 (UniProt: C4TPE0)

PDB	External Database	Details
Met 6	-	initiating methionine
His 265	-	expression tag
His 266	-	expression tag
His 267	-	expression tag
His 268	-	expression tag
His 269	-	expression tag
His 270	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29948.4
Non-Polymers*	Number of molecules	6
	Total formula weight	1351.3
All*	Total formula weight	31299.7

*Water molecules are not included.