7V0Z
Factor XIa in Complex with Compound 2a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Coagulation factor XIa light chain | polymer | 238 | 26856.5 | 1 | UniProt (P03951) Pfam (PF00089) In PDB | Homo sapiens (human) | FXI,Plasma thromboplastin antecedent,PTA |
| 2 | A | methyl ~{N}-[4-[1-[(1~{R})-1-[5-[5-chloranyl-2-(1,2,3,4-tetrazol-1-yl)phenyl]-1-oxidanyl-pyridin-2-yl]-2-cyclopropyl-ethyl]pyrazol-4-yl]phenyl]carbamate | non-polymer | 557.0 | 1 | Chemie (OQ6) | |||
| 3 | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A: 388 - 625 (UniProt: P03951)
| PDB | External Database | Details |
|---|---|---|
| Ser 500 | Cys 500 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26856.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 557.0 | |
| All* | Total formula weight | 27413.5 |
