7UZ9
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-34
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Spike glycoprotein | polymer | 1256 | 139344.4 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
2 | H, M, P | M8a-34 Fab heavy chain | polymer | 235 | 25507.5 | 3 | Mus musculus | ||
3 | L, N, Q | M8a-34 Fab light chain | polymer | 218 | 23955.6 | 3 | Mus musculus | ||
4 | B, A, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 42 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1213 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
- | Arg 682 | deletion |
- | Arg 683 | deletion |
- | Arg 685 | deletion |
Pro 817 | Phe 817 | engineered mutation |
Pro 892 | Ala 892 | engineered mutation |
Pro 899 | Ala 899 | engineered mutation |
Pro 942 | Ala 942 | engineered mutation |
Pro 986 | Lys 986 | engineered mutation |
Pro 987 | Val 987 | engineered mutation |
Ser 1214 | - | expression tag |
Gly 1215 | - | expression tag |
Arg 1216 | - | expression tag |
Leu 1217 | - | expression tag |
Val 1218 | - | expression tag |
Pro 1219 | - | expression tag |
Arg 1220 | - | expression tag |
Gly 1221 | - | expression tag |
Ser 1222 | - | expression tag |
Pro 1223 | - | expression tag |
Gly 1224 | - | expression tag |
Ser 1225 | - | expression tag |
Gly 1226 | - | expression tag |
Tyr 1227 | - | expression tag |
Ile 1228 | - | expression tag |
Pro 1229 | - | expression tag |
Glu 1230 | - | expression tag |
Ala 1231 | - | expression tag |
Pro 1232 | - | expression tag |
Arg 1233 | - | expression tag |
Asp 1234 | - | expression tag |
Gly 1235 | - | expression tag |
Gln 1236 | - | expression tag |
Ala 1237 | - | expression tag |
Tyr 1238 | - | expression tag |
Val 1239 | - | expression tag |
Arg 1240 | - | expression tag |
Lys 1241 | - | expression tag |
Asp 1242 | - | expression tag |
Gly 1243 | - | expression tag |
Glu 1244 | - | expression tag |
Trp 1245 | - | expression tag |
Val 1246 | - | expression tag |
Leu 1247 | - | expression tag |
Leu 1248 | - | expression tag |
Ser 1249 | - | expression tag |
Thr 1250 | - | expression tag |
Phe 1251 | - | expression tag |
Leu 1252 | - | expression tag |
Gly 1253 | - | expression tag |
His 1254 | - | expression tag |
His 1255 | - | expression tag |
His 1256 | - | expression tag |
His 1257 | - | expression tag |
His 1258 | - | expression tag |
His 1259 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 9 |
Total formula weight | 566422.6 | |
Non-Polymers* | Number of molecules | 42 |
Total formula weight | 9290.7 | |
All* | Total formula weight | 575713.3 |