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7UYT

Crystal structure of TYK2 kinase domain in complex with compound 25

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ANon-receptor tyrosine-protein kinase TYK2polymer28933643.41UniProt (P29597)
Pfam (PF07714)
In PDB
Homo sapiens (human)
2A6-{[(2M)-2-(2-chloro-6-fluorophenyl)-5-oxo-5H-pyrrolo[3,4-b]pyridin-4-yl]amino}-N-ethylpyridine-3-carboxamidenon-polymer423.81Chemie (OV5)
3waterwater18.063Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33643.4
Non-Polymers*Number of molecules1
Total formula weight423.8
All*Total formula weight34067.2
*Water molecules are not included.

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PDB entries from 2024-05-22

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