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7UYS

Crystal structure of TYK2 kinase domain in complex with compound 16

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ANon-receptor tyrosine-protein kinase TYK2polymer28933643.41UniProt (P29597)
Pfam (PF07714)
In PDB
Homo sapiens (human)
2A2-(2,6-difluorophenyl)-4-(4-methoxyanilino)-5H-pyrrolo[3,4-d]pyrimidin-5-onenon-polymer366.31Chemie (OVC)
3waterwater18.064Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33643.4
Non-Polymers*Number of molecules1
Total formula weight366.3
All*Total formula weight34009.7
*Water molecules are not included.

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PDB entries from 2024-08-21

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