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7UYR

Crystal structure of TYK2 kinase domain in complex with compound 12

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ANon-receptor tyrosine-protein kinase TYK2polymer28933643.41UniProt (P29597)
Pfam (PF07714)
In PDB
Homo sapiens (human)
2A2-(4-{[2-(2,6-difluorophenyl)-5-oxo-5H-pyrrolo[3,4-d]pyrimidin-4-yl]amino}phenyl)-N-ethylacetamidenon-polymer421.41Chemie (OVI)
3waterwater18.083Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33643.4
Non-Polymers*Number of molecules1
Total formula weight421.4
All*Total formula weight34064.8
*Water molecules are not included.

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PDB entries from 2024-06-12

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