7UYR
Crystal structure of TYK2 kinase domain in complex with compound 12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Non-receptor tyrosine-protein kinase TYK2 | polymer | 289 | 33643.4 | 1 | UniProt (P29597) Pfam (PF07714) | Homo sapiens (human) | |
| 2 | B (A) | 2-(4-{[2-(2,6-difluorophenyl)-5-oxo-5H-pyrrolo[3,4-d]pyrimidin-4-yl]amino}phenyl)-N-ethylacetamide | non-polymer | 421.4 | 1 | Chemie (OVI) | |||
| 3 | C (A) | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33643.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 421.4 | |
| All* | Total formula weight | 34064.8 |
