7UYR
Crystal structure of TYK2 kinase domain in complex with compound 12
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Non-receptor tyrosine-protein kinase TYK2 | polymer | 289 | 33643.4 | 1 | UniProt (P29597) Pfam (PF07714) In PDB | Homo sapiens (human) | |
2 | A | 2-(4-{[2-(2,6-difluorophenyl)-5-oxo-5H-pyrrolo[3,4-d]pyrimidin-4-yl]amino}phenyl)-N-ethylacetamide | non-polymer | 421.4 | 1 | Chemie (OVI) | |||
3 | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33643.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 421.4 | |
All* | Total formula weight | 34064.8 |