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7UYO

Crystal structure of B-form alien DNA 5'-CTTSSPBZPSZBBAAG in a host-guest complex with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
reverse transcriptasepolymer26630023.51UniProt (Q8UN00)
Pfam (PF00078)
UniProt (by SIFTS) (P03355)
Moloney murine leukemia virus
2B
(B)
DNA (5'-D(*CP*TP*TP*(JSP)P*(JSP)P*(1WA)P*(IGU)P*(1W5))-3')polymer82452.61synthetic construct
3C
(G)
DNA (5'-D(P*(1WA)P*(JSP)P*(1W5)P*(IGU)P*(IGU)P*AP*AP*G)-3')polymer82536.71synthetic construct
4D, E, F
(A, B, G)
waterwater18.0154Chemie (HOH)
Sequence modifications
A: 24 - 278 (UniProt: Q8UN00)
PDBExternal DatabaseDetails
Gly 20-expression tag
Ser 21-expression tag
His 22-expression tag
Met 23-expression tag
Asn 249Asp 908conflict
Leu 279-expression tag
Thr 280-expression tag
Arg 281-expression tag
Gly 282-expression tag
Ser 283-expression tag
Gly 284-expression tag
Cys 285-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight35012.9
All*Total formula weight35012.9
*Water molecules are not included.

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PDB entries from 2025-02-05

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