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7UX8

Crystal structure of MfnG, an L- and D-tyrosine O-methyltransferase from the marformycin biosynthesis pathway of Streptomyces drozdowiczii, with SAH and L-Tyrosine bound at 1.4 A resolution (P212121 - form II)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
MfnGpolymer38442042.22UniProt (A0A0D4WTP2)
Pfam (PF00891)
Streptomyces drozdowiczii
2C, F
(A, B)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
3D, G
(A, B)
TYROSINEnon-polymer181.22Chemie (TYR)
4E, H
(A, B)
UNKNOWN LIGANDnon-polymer2Chemie (UNL)
5I, J
(A, B)
waterwater18.0798Chemie (HOH)
Sequence modifications
A, B: 2 - 375 (UniProt: A0A0D4WTP2)
PDBExternal DatabaseDetails
Met 0-cloning artifact
Val 1-cloning artifact
Ala 376-expression tag
Ser 377-expression tag
Glu 378-expression tag
Asn 379-expression tag
Leu 380-expression tag
Tyr 381-expression tag
Phe 382-expression tag
Gln 383-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight84084.5
Non-Polymers*Number of molecules6
Total formula weight1131.2
All*Total formula weight85215.7
*Water molecules are not included.

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PDB entries from 2025-12-10

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