7UWP

Detergent-bound CYP51 from Acanthamoeba castellanii

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	sterol 14a-demethylase	polymer	460	52447.3	2	UniProt (L8GJB3) Pfam (PF00067) In PDB	Acanthamoeba castellanii	Obtusifoliol 14alphademethylase, putative
2	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	A, B	DODECYL-BETA-D-MALTOSIDE	non-polymer		510.6	2	Chemie (LMT)
4		water	water		18.0	784	Chemie (HOH)

Sequence modifications

A, B: 43 - 486 (UniProt: L8GJB3)

PDB	External Database	Details
Met 33	-	initiating methionine
Ala 34	-	expression tag
Lys 35	-	expression tag
Lys 36	-	expression tag
Thr 37	-	expression tag
Ser 38	-	expression tag
Ser 39	-	expression tag
Lys 40	-	expression tag
Gly 41	-	expression tag
Lys 42	-	expression tag
His 487	-	expression tag
His 488	-	expression tag
His 489	-	expression tag
His 490	-	expression tag
His 491	-	expression tag
His 492	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	104894.6
Non-Polymers*	Number of molecules	4
	Total formula weight	2254.2
All*	Total formula weight	107148.9

*Water molecules are not included.