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7UW4

Crystal structure of human Retinoid X receptor alpha ligand binding domain complex with UAB113 and coactivator peptide GRIP-1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Retinoic acid receptor RXR-alphapolymer24026856.01UniProt (P19793)
Pfam (PF00104)
Homo sapiens (human)Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha
2B
(B)
Nuclear receptor coactivator 2polymer131579.91UniProt (Q15596)Homo sapiensNCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2
3C
(A)
(2E,4E,6Z,8E)-3,7-dimethyl-8-[2-(3-methylbutyl)-3-propylcyclohex-2-en-1-ylidene]octa-2,4,6-trienoic acidnon-polymer356.51Chemie (OI5)
4D, E
(A, B)
waterwater18.034Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28435.9
Non-Polymers*Number of molecules1
Total formula weight356.5
All*Total formula weight28792.4
*Water molecules are not included.

229564

PDB entries from 2025-01-01

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