7UVM
Crystal structure of human ClpP protease in complex with TR-27
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | ATP-dependent Clp protease proteolytic subunit, mitochondrial | polymer | 221 | 24179.9 | 7 | UniProt (Q16740) Pfam (PF00574) | Homo sapiens (human) | Endopeptidase Clp |
| 2 | H, I, J, K, L... (A, B, C, D, E...) | (10R)-4-[(4-chlorophenyl)methyl]-7-[(3-ethynylphenyl)methyl]-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one | non-polymer | 430.9 | 7 | Chemie (OX0) | |||
| 3 | O, P, Q, R, S... (A, B, C, D, E...) | water | water | 18.0 | 428 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G: 58 - 277 (UniProt: Q16740)
| PDB | External Database | Details |
|---|---|---|
| Ser 57 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 169259.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 3016.5 | |
| All* | Total formula weight | 172275.6 |
