7UVF

Crystal structure of ZED8 Fab complex with CD8 alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	T-cell surface glycoprotein CD8 alpha chain	polymer	128	14425.2	2	UniProt (P01732) Pfam (PF07686)	Homo sapiens (human)	T-lymphocyte differentiation antigen T8/Leu-2
2	C, F (H, X)	Immunoglobulin heavy chain	polymer	221	23474.2	2		Homo sapiens
3	D, E (L, Y)	Immunoglobulin light chain	polymer	214	23437.9	2		Homo sapiens
4	G (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	H, I (H, X)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	J, K, L, M, N... (A, B, H, L, Y...)	water	water		18.0	172	Chemie (HOH)

Sequence modifications

A, B: 1 - 120 (UniProt: P01732)

PDB	External Database	Details
Gly 121	-	expression tag
Asn 122	-	expression tag
Ser 123	-	expression tag
His 124	-	expression tag
His 125	-	expression tag
His 126	-	expression tag
His 127	-	expression tag
His 128	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	122674.8
Non-Polymers*	Number of molecules	3
	Total formula weight	163.0
All*	Total formula weight	122837.8

*Water molecules are not included.