7UUT
Ternary complex crystal structure of secondary alcohol dehydrogenases from the Thermoanaerobacter ethanolicus mutants C295A and I86A provides better understanding of catalytic mechanism
Replaces: 7JNUEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Secondary-alcohol dehydrogenase | polymer | 352 | 37652.8 | 1 | UniProt (P14941) Pfam (PF08240) Pfam (PF00107) UniProt (by SIFTS) (P77990) | Thermoanaerobacter pseudethanolicus | |
| 2 | B, C, D (B, C, D) | Secondary-alcohol dehydrogenase | polymer | 352 | 37680.8 | 3 | UniProt (P14941) Pfam (PF08240) Pfam (PF00107) UniProt (by SIFTS) (P77990) | Thermoanaerobacter pseudethanolicus | |
| 3 | E, I, M, Q (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | F, J, N, R (A, B, C, D) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
| 5 | G, K, O, S (A, B, C, D) | (2R)-pentan-2-ol | non-polymer | 88.1 | 4 | Chemie (2RP) | |||
| 6 | H, L, P, T (A, B, C, D) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 7 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 358 | Chemie (HOH) |
Sequence modifications
A: 1 - 352 (UniProt: P14941)
B, C, D: 1 - 352 (UniProt: P14941)
| PDB | External Database | Details |
|---|---|---|
| Ala 86 | Ile 86 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 86 | Ile 86 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 150695.2 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3744.2 | |
| All* | Total formula weight | 154439.4 |
