7UU0
Crystal structure of the BRD2-BD2 in complex with a ligand
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Isoform 3 of Bromodomain-containing protein 2 | polymer | 135 | 15847.1 | 1 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (human) | O27.1.1,Really interesting new gene 3 protein |
2 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
3 | A | methyl (7S)-7-(thiophen-2-yl)-1,4-thiazepane-4-carboxylate | non-polymer | 257.4 | 1 | Chemie (QJ1) | |||
4 | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence modifications
A: 344 - 455 (UniProt: P25440)
PDB | External Database | Details |
---|---|---|
Met 321 | - | expression tag |
His 322 | - | expression tag |
His 323 | - | expression tag |
His 324 | - | expression tag |
His 325 | - | expression tag |
His 326 | - | expression tag |
His 327 | - | expression tag |
Ser 328 | - | expression tag |
Ser 329 | - | expression tag |
Gly 330 | - | expression tag |
Val 331 | - | expression tag |
Asp 332 | - | expression tag |
Leu 333 | - | expression tag |
Gly 334 | - | expression tag |
Thr 335 | - | expression tag |
Glu 336 | - | expression tag |
Asn 337 | - | expression tag |
Leu 338 | - | expression tag |
Tyr 339 | - | expression tag |
Phe 340 | - | expression tag |
Gln 341 | - | expression tag |
Ser 342 | - | expression tag |
Met 343 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 15847.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 319.4 | |
All* | Total formula weight | 16166.5 |