7UTC
Crystal structure of secondary alcohol dehydrogenases from the Thermoanaerobacter ethanolicus with NADP and transition-state analogue inhibitor DMSO
Replaces: 7JNQEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Secondary-alcohol dehydrogenase | polymer | 352 | 37662.8 | 4 | UniProt (P14941) Pfam (PF08240) Pfam (PF00107) In PDB | Thermoanaerobacter pseudethanolicus | |
| 2 | A, D, B, C | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | C, A, D, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
| 4 | C, A, D, B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 35 | Chemie (DMS) | |||
| 5 | water | water | 18.0 | 492 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 352 (UniProt: P14941)
| PDB | External Database | Details |
|---|---|---|
| Ala 295 | Cys 295 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 150651.2 | |
| Non-Polymers* | Number of molecules | 43 |
| Total formula weight | 5969.9 | |
| All* | Total formula weight | 156621.1 |
