7UTC

Crystal structure of secondary alcohol dehydrogenases from the Thermoanaerobacter ethanolicus with NADP and transition-state analogue inhibitor DMSO

Replaces:  7JNQ

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Secondary-alcohol dehydrogenase	polymer	352	37662.8	4	UniProt (P14941) Pfam (PF08240) Pfam (PF00107)	Thermoanaerobacter pseudethanolicus
2	E, LA, P, Z (A, D, B, C)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	AA, F, MA, Q (C, A, D, B)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	4	Chemie (NAP)
4	BA, CA, DA, EA, FA... (C, A, D, B)	DIMETHYL SULFOXIDE	non-polymer		78.1	35	Chemie (DMS)
5	VA, WA, XA, YA (A, B, C, D)	water	water		18.0	492	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 352 (UniProt: P14941)

PDB	External Database	Details
Ala 295	Cys 295	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	150651.2
Non-Polymers*	Number of molecules	43
	Total formula weight	5969.9
All*	Total formula weight	156621.1

*Water molecules are not included.