7USJ

BRD4-BD2 in complex with SF2523

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Bromodomain-containing protein 4	polymer	109	12735.9	2	UniProt (O60885) Pfam (PF00439)	Homo sapiens (human)	Protein HUNK1
2	C, D (A, B)	3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(morpholin-4-yl)-7H-thieno[3,2-b]pyran-7-one	non-polymer		371.4	2	Chemie (82V)
3	E, F (A, B)	water	water		18.0	116	Chemie (HOH)

Sequence modifications

A, B: 352 - 457 (UniProt: O60885)

PDB	External Database	Details
Gly 349	-	expression tag
Pro 350	-	expression tag
Met 351	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	25471.7
Non-Polymers*	Number of molecules	2
	Total formula weight	742.8
All*	Total formula weight	26214.6

*Water molecules are not included.