7US6

Structure of the human coronavirus CCoV-HuPn-2018 spike glycoprotein with domain 0 in the proximal conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Spike glycoprotein	polymer	1295	142666.4	3	UniProt (A0A8E6CMP0) Pfam (PF01600) Pfam (PF19209) Pfam (PF01601) In PDB	unidentified human coronavirus	S glycoprotein,E2,Peplomer protein
2	a, b, c, D, F...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	20	In PDB GlyTouCan (G42666HT)
3	E, N, V	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	3	In PDB GlyTouCan (G22768VO)
4	H, Q, Y	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose	branched		504.4	3	In PDB GlyTouCan (G72618IM)
5	B, A, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	43	Chemie (NAG)

Sequence modifications

A, B, C: 205 - 1392 (UniProt: A0A8E6CMP0)

PDB	External Database	Details
His 32	-	expression tag
Trp 33	-	expression tag
Asn 34	-	expression tag
Leu 35	-	expression tag
Ile 36	-	expression tag
Glu 37	-	expression tag
Asn 38	-	expression tag
Phe 39	-	expression tag
Leu 40	-	expression tag
Leu 41	-	expression tag
Asn 42	-	expression tag
Tyr 43	-	expression tag
Ser 44	-	expression tag
Ile 45	-	expression tag
Arg 46	-	expression tag
Leu 47	-	expression tag
Pro 48	-	expression tag
Pro 49	-	expression tag
Asn 50	-	expression tag
Ser 51	-	expression tag
Asp 52	-	expression tag
Val 53	-	expression tag
Val 54	-	expression tag
Leu 55	-	expression tag
Gly 56	-	expression tag
Asp 57	-	expression tag
Tyr 58	-	expression tag
Phe 59	-	expression tag
Pro 60	-	expression tag
Thr 61	-	expression tag
Val 62	-	expression tag
Gln 190	-	expression tag
Pro 191	-	expression tag
Trp 192	-	expression tag
Phe 193	-	expression tag
Asn 194	-	expression tag
Cys 195	-	expression tag
Ile 196	-	expression tag
Arg 197	-	expression tag
Asn 198	-	expression tag
Asn 199	-	expression tag
Asn 200	-	expression tag
Asn 201	-	expression tag
Ser 202	-	expression tag
Leu 203	-	expression tag
Tyr 204	-	expression tag
Met 207	Leu 207	conflict
Glu 208	Gly 208	conflict
Asn 209	Asp 209	conflict
Leu 210	Met 210	conflict
Lys 211	Arg 211	conflict
Leu 213	Thr 213	conflict
Tyr 214	Thr 214	conflict
Trp 215	Leu 215	conflict
Asp 216	Gln 216	conflict
Tyr 217	Thr 217	conflict
Thr 219	Gly 219	conflict
Glu 220	Ala 220	conflict
Asn 221	Leu 221	conflict
Ile 222	Val 222	conflict
Thr 223	Asp 223	conflict
Ser 224	Leu 224	conflict
Asp 225	Trp 225	conflict
His 226	Trp 226	conflict
Arg 227	Phe 227	conflict
Gln 228	Asn 228	conflict
Pro 1140	Glu 1140	conflict
Pro 1141	Leu 1141	conflict
Ser 1388	Trp 1388	conflict
Gly 1389	Pro 1389	conflict
Gly 1390	Trp 1390	conflict
Ile 1392	Val 1392	conflict
Pro 1393	-	expression tag
Glu 1394	-	expression tag
Ala 1395	-	expression tag
Pro 1396	-	expression tag
Arg 1397	-	expression tag
Asp 1398	-	expression tag
Gly 1399	-	expression tag
Gln 1400	-	expression tag
Ala 1401	-	expression tag
Tyr 1402	-	expression tag
Val 1403	-	expression tag
Arg 1404	-	expression tag
Lys 1405	-	expression tag
Asp 1406	-	expression tag
Gly 1407	-	expression tag
Glu 1408	-	expression tag
Trp 1409	-	expression tag
Val 1410	-	expression tag
Leu 1411	-	expression tag
Leu 1412	-	expression tag
Ser 1413	-	expression tag
Thr 1414	-	expression tag
Phe 1415	-	expression tag
Leu 1416	-	expression tag
Val 1417	-	expression tag
Pro 1418	-	expression tag
Arg 1419	-	expression tag
Gly 1420	-	expression tag
Ser 1421	-	expression tag
Gly 1422	-	expression tag
Gly 1423	-	expression tag
Ser 1424	-	expression tag
Gly 1425	-	expression tag
Gly 1426	-	expression tag
Ser 1427	-	expression tag
Gly 1428	-	expression tag
Leu 1429	-	expression tag
Asn 1430	-	expression tag
Asp 1431	-	expression tag
Ile 1432	-	expression tag
Phe 1433	-	expression tag
Glu 1434	-	expression tag
Ala 1435	-	expression tag
Gln 1436	-	expression tag
Lys 1437	-	expression tag
Ile 1438	-	expression tag
Glu 1439	-	expression tag
Trp 1440	-	expression tag
His 1441	-	expression tag
Glu 1442	-	expression tag
Gly 1443	-	expression tag
Gly 1444	-	expression tag
Ser 1445	-	expression tag
His 1446	-	expression tag
His 1447	-	expression tag
His 1448	-	expression tag
His 1449	-	expression tag
His 1450	-	expression tag
His 1451	-	expression tag
His 1452	-	expression tag
His 1453	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	427999.2
Branched	Number of molecules	26
	Total formula weight	12733.8
Non-Polymers*	Number of molecules	43
	Total formula weight	9511.9
All*	Total formula weight	450244.9

*Water molecules are not included.