7US5

X-ray crystal structure of GDP-D-glycero-D-manno-heptose 4,6-Dehydratase from Campylobacter jejuni

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	GDP-D-GLYCERO-D-MANNO-HEPTOSE 4,6-DEHYDRATASE	polymer	365	41608.3	4	UniProt (Q5M6Q7)	Campylobacter jejuni	GDP-mannose 4,6-dehydratase, GDP-D-GLYCERO-D-MANNO-HEPTOSE 4,6-DEHYDRATASE,SDR FAMILY
2	E, H, K, P (A, B, C, D)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	4	Chemie (NAD)
3	F, I, L, Q (A, B, C, D)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	4	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
4	G, J, M, N, O... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
5	S, T, U, V (A, B, C, D)	water	water		18.0	937	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 345 (UniProt: Q5M6Q7)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Met 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	166433.2
Non-Polymers*	Number of molecules	14
	Total formula weight	4798.9
All*	Total formula weight	171232.2

*Water molecules are not included.