7URS

Crystal Structure of SARS-CoV-2 S delta variant receptor-binding domain (RBD) in complex CoV11 Fab crystal form 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Spike protein S1	polymer	231	26167.5	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
2	H	COV11 Fab HEAVY CHAIN	polymer	221	23362.3	1		Homo sapiens
3	L	COV11 Fab HEAVY CHAIN	polymer	216	23536.0	1		Homo sapiens
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	A	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
6	A, L	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
7		water	water		18.0	85	Chemie (HOH)

Sequence modifications

A: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Arg 452	Leu 452	engineered mutation
Lys 478	Thr 478	engineered mutation
Ser 542	-	expression tag
Gly 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
His 549	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	73065.8
Non-Polymers*	Number of molecules	5
	Total formula weight	647.5
All*	Total formula weight	73713.3

*Water molecules are not included.