7URQ

Crystal Structure of SARS-CoV-2 S delta variant receptor-binding domain (RBD) in complex CoV11 Fab crystal form 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Spike protein S1	polymer	229	25946.2	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
2	H	COV11 Fab HEAVY CHAIN	polymer	221	23362.3	1		Homo sapiens
3	L	COV11 Fab LIGHT CHAIN	polymer	216	23536.0	1		Homo sapiens
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	H	CITRIC ACID	non-polymer		192.1	1	Chemie (CIT)
6		water	water		18.0	243	Chemie (HOH)

Sequence modifications

A: 319 - 537 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 317	-	expression tag
Ser 318	-	expression tag
Arg 452	Leu 452	engineered mutation
Lys 478	Thr 478	engineered mutation
Leu 538	-	expression tag
Glu 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	72844.5
Non-Polymers*	Number of molecules	2
	Total formula weight	413.3
All*	Total formula weight	73257.8

*Water molecules are not included.