7URQ
Crystal Structure of SARS-CoV-2 S delta variant receptor-binding domain (RBD) in complex CoV11 Fab crystal form 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Spike protein S1 | polymer | 229 | 25946.2 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
| 2 | B (H) | COV11 Fab HEAVY CHAIN | polymer | 221 | 23362.3 | 1 | Homo sapiens | ||
| 3 | C (L) | COV11 Fab LIGHT CHAIN | polymer | 216 | 23536.0 | 1 | Homo sapiens | ||
| 4 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E (H) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 6 | F, G, H (A, H, L) | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence modifications
A: 319 - 537 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 317 | - | expression tag |
| Ser 318 | - | expression tag |
| Arg 452 | Leu 452 | engineered mutation |
| Lys 478 | Thr 478 | engineered mutation |
| Leu 538 | - | expression tag |
| Glu 539 | - | expression tag |
| His 540 | - | expression tag |
| His 541 | - | expression tag |
| His 542 | - | expression tag |
| His 543 | - | expression tag |
| His 544 | - | expression tag |
| His 545 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 72844.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 413.3 | |
| All* | Total formula weight | 73257.8 |
