7UP2
NDM1-inhibitor co-structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase VIM-1 | polymer | 246 | 26009.8 | 1 | UniProt (Q9XAY4) Pfam (PF00753) | Pseudomonas aeruginosa | Class B carbapenemase VIM-1,Metallo-beta-lactamase,Metallo-beta-lactamase VIM-1,Metallobeta-lactamase,Subclass B1 metallo-beta-lactamase VIM-1,VIM-1,VIM-1 metallo-beta-lactamase,VIM-1 protein |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | (2M)-4'-methyl-2-(2H-tetrazol-5-yl)[1,1'-biphenyl]-3-sulfonamide | non-polymer | 315.4 | 1 | Chemie (NZR) | |||
| 4 | E (A) | water | water | 18.0 | 265 | Chemie (HOH) |
Sequence modifications
A: 27 - 266 (UniProt: Q9XAY4)
| PDB | External Database | Details |
|---|---|---|
| Gly 21 | - | expression tag |
| Ser 22 | - | expression tag |
| Lys 23 | - | expression tag |
| Leu 24 | - | expression tag |
| Glu 25 | - | expression tag |
| Phe 26 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26009.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 446.2 | |
| All* | Total formula weight | 26456.0 |
