7UOR

Crystal structure of cytochrome P450 enzyme CYP119 in complex with methyliridium(III) mesoporphyrin.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Cytochrome	polymer	385	45049.2	6	UniProt (A0A0U3HD14) Pfam (PF00067) UniProt (by SIFTS) (Q55080) In PDB	Sulfolobus acidocaldarius
2	A, B, C, D, E...	methyliridium(III) mesoporphyrin	non-polymer		780.9	6	Chemie (HIR)
3	A, B, C, D, E...	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	6	Chemie (BTB)
4	A, D	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI)

Sequence modifications

A, B, C, D, E, F: 2 - 368 (UniProt: A0A0U3HD14)

PDB	External Database	Details
Met -16	-	initiating methionine
Lys -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag
Asn 1	-	expression tag
Trp 155	Leu 155	engineered mutation
Gly 213	Thr 213	engineered mutation
Leu 254	Val 254	engineered mutation
Gly 317	Cys 317	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	270295.3
Non-Polymers*	Number of molecules	14
	Total formula weight	6058.0
All*	Total formula weight	276353.4

*Water molecules are not included.