7UOB
SARS-CoV-2 replication-transcription complex bound to GTP, in a pre-catalytic state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | RNA-directed RNA polymerase | polymer | 932 | 106781.0 | 1 | UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680) In PDB | Severe acute respiratory syndrome coronavirus 2 | Pol, RdRp, Non-structural protein 12, nsp12 |
2 | B, D | Non-structural protein 8 | polymer | 198 | 21903.0 | 2 | UniProt (P0DTD1) Pfam (PF08717) In PDB | Severe acute respiratory syndrome coronavirus 2 | nsp8 |
3 | C | Non-structural protein 7 | polymer | 92 | 10250.0 | 1 | UniProt (P0DTD1) Pfam (PF08716) In PDB | Severe acute respiratory syndrome coronavirus 2 | nsp7 |
4 | P | Product RNA (35-MER) | polymer | 35 | 11155.7 | 1 | synthetic construct | ||
5 | T | Template RNA (55-MER) | polymer | 55 | 17557.3 | 1 | synthetic construct | ||
6 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
7 | A | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
8 | A | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
9 | P | 3'-DEOXYURIDINE-5'-MONOPHOSPHATE | non-polymer | 308.2 | 1 | Chemie (L2B) | |||
10 | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence modifications
C: 1 - 83 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Val -8 | - | expression tag |
Ala -7 | - | expression tag |
Cys -6 | - | expression tag |
Thr -5 | - | expression tag |
Lys -4 | - | expression tag |
Glu -3 | - | expression tag |
Val -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 189550.1 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1558.3 | |
All* | Total formula weight | 191108.4 |