7UL5

CryoEM Structure of Inactive SSTR2 bound to Nb6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Somatostatin receptor type 2	polymer	414	46542.1	1	UniProt (P30874) UniProt (P41145) Pfam (PF00001)	Homo sapiens (human)	SS-2-R,SS2-R,SS2R,SRIF-1,K-OR-1,KOR-1
2	B (D)	Nanobody 6	polymer	133	14730.3	1		Lama glama

Sequence modifications

A: 1 - 237 (UniProt: P30874)

PDB	External Database	Details
Asp -38	-	expression tag
Tyr -37	-	expression tag
Lys -36	-	expression tag
Asp -35	-	expression tag
Asp -34	-	expression tag
Asp -33	-	expression tag
Asp -32	-	expression tag
Ala -31	-	expression tag
Met -30	-	expression tag
Gly -29	-	expression tag
Gln -28	-	expression tag
Pro -27	-	expression tag
Gly -26	-	expression tag
Asn -25	-	expression tag
Gly -24	-	expression tag
Ser -23	-	expression tag
Ala -22	-	expression tag
Phe -21	-	expression tag
Leu -20	-	expression tag
Leu -19	-	expression tag
Ala -18	-	expression tag
Pro -17	-	expression tag
Asn -16	-	expression tag
Arg -15	-	expression tag
Ser -14	-	expression tag
His -13	-	expression tag
Ala -12	-	expression tag
Pro -11	-	expression tag
Asp -10	-	expression tag
His -9	-	expression tag
Asp -8	-	expression tag
Val -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

A: 238 - 253 (UniProt: P41145)
A: 254 - 369 (UniProt: P30874)

PDB	External Database	Details
Leu 370	-	expression tag
Glu 371	-	expression tag
Val 372	-	expression tag
Leu 373	-	expression tag
Phe 374	-	expression tag
Gln 375	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61272.3
All*	Total formula weight	61272.3

*Water molecules are not included.