7UKL
Cryo-EM structure of Antibody 12-16 in complex with prefusion SARS-CoV-2 Spike glycoprotein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | Y, L, N | 12-16 Fab Light Chain | polymer | 108 | 11669.8 | 3 | Homo sapiens (Human) | ||
| 2 | B, C, A | Spike glycoprotein | polymer | 1273 | 141205.3 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 3 | X, H, M | 12-16 Fab Heavy Chain | polymer | 132 | 14604.1 | 3 | Homo sapiens (Human) | ||
| 4 | C, A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 48 | Chemie (NAG) |
Sequence modifications
B, C, A: 1 - 1273 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 614 | Asp 614 | engineered mutation |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 502437.5 | |
| Non-Polymers* | Number of molecules | 48 |
| Total formula weight | 10618.0 | |
| All* | Total formula weight | 513055.5 |
