Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7UJP

Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B

Replaces:  6XBX
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BCalcium/calmodulin-dependent protein kinase type II subunit alphapolymer26830548.12UniProt (Q9UQM7)
Pfam (PF00069)
In PDB
Homo sapiens (human)CaMK-II subunit alpha
2C, DGlutamate receptor ionotropic, NMDA 2Bpolymer222754.22UniProt (Q13224)
In PDB
Homo sapiensGluN2B,Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B,NR2B,N-methyl-D-aspartate receptor subunit 3,hNR3
3AADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
4A, B, CMAGNESIUM IONnon-polymer24.33Chemie (MG)
5BADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
6BGLYCEROLnon-polymer92.11Chemie (GOL)
7waterwater18.045Chemie (HOH)
Sequence modifications
A, B: 7 - 274 (UniProt: Q9UQM7)
PDBExternal DatabaseDetails
Asn 135Asp 135engineered mutation
Lys 223Gln 223engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight66604.5
Non-Polymers*Number of molecules6
Total formula weight1099.4
All*Total formula weight67703.9
*Water molecules are not included.

225946

PDB entries from 2024-10-09

PDB statisticsPDBj update infoContact PDBjnumon