7UJG
Room-temperature X-ray structure of monomeric SARS-CoV-2 main protease catalytic domain (MPro1-196) in complex with GC-376
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3C-like proteinase nsp5 | polymer | 191 | 21040.1 | 2 | UniProt (P0DTC1) Pfam (PF05409) UniProt (by SIFTS) (P0DTD1) | Severe acute respiratory syndrome coronavirus 2 | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 2 | C, D (A, B) | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid | non-polymer | 485.6 | 2 | BIRD (PRD_002495) Chemie (K36) PubChem (71481120) PubChem (131704476) PubChem (172472623) PubChem (77987125) PubChem (118737648) PubChem (131704478) PubChem (137348969) PubChem (137349627) PubChem (138734767) PubChem (156198974) PubChem (162651992) PubChem (163337713) PubChem (169544973) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42080.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 971.1 | |
| All* | Total formula weight | 43051.3 |
