7UIQ

Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and Tiam1

Replaces: 6X8V

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Calcium/calmodulin-dependent protein kinase type II subunit alpha	polymer	268	30548.1	2	UniProt (Q9UQM7) Pfam (PF00069)	Homo sapiens (human)	CaMK-II subunit alpha
2	C, D (C, D)	T-lymphoma invasion and metastasis-inducing protein 1	polymer	19	2160.5	2	UniProt (Q60610)	Mus musculus	TIAM-1

Sequence modifications

A, B: 7 - 274 (UniProt: Q9UQM7)

PDB	External Database	Details
Asn 135	Asp 135	engineered mutation
Lys 223	Gln 223	engineered mutation

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.