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7UIQ

Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and Tiam1

Replaces:  6X8V
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BCalcium/calmodulin-dependent protein kinase type II subunit alphapolymer26830548.12UniProt (Q9UQM7)
Pfam (PF00069)
In PDB
Homo sapiens (human)CaMK-II subunit alpha
2C, DT-lymphoma invasion and metastasis-inducing protein 1polymer192160.52UniProt (Q60610)
In PDB
Mus musculusTIAM-1
Sequence modifications
A, B: 7 - 274 (UniProt: Q9UQM7)
PDBExternal DatabaseDetails
Asn 135Asp 135engineered mutation
Lys 223Gln 223engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight65417.2
All*Total formula weight65417.2
*Water molecules are not included.

223166

PDB entries from 2024-07-31

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