7UIB
Crystal structure of BoNT/E receptor binding domain in complex with SV2, VHH, and sialic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (B, E) | VHH-G6 | polymer | 129 | 14390.9 | 2 | Vicugna pacos | ||
| 2 | B, D (C, F) | SV2 | polymer | 105 | 12198.5 | 2 | Pfam (PF13599) UniProt (by SIFTS) (Q496J9) | Homo sapiens | |
| 3 | E, F (D, A) | Neurotoxin type E | polymer | 407 | 47392.8 | 2 | UniProt (A5H0J8) Pfam (PF07953) Pfam (PF07951) UniProt (by SIFTS) (Q00496) | Clostridium botulinum | |
| 4 | G, H (G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | I, L, M, N (C, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 6 | J, K, P, R, S... (C, F, D, A) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 7 | O (F) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 8 | Q, T (D, A) | N-acetyl-beta-neuraminic acid | non-polymer | 309.3 | 2 | Chemie (SLB) | |||
| 9 | AA, BA, W, X, Y... (D, A, B, C, E...) | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 147964.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2370.0 | |
| All* | Total formula weight | 151183.4 |
