7UI5
Evolution avoids a pathological stabilizing interaction in the immune protein S100A9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein S100-A9 | polymer | 114 | 13263.9 | 2 | UniProt (P06702) Pfam (PF01023) | Homo sapiens (human) | Calgranulin-B,Calprotectin L1H subunit,Leukocyte L1 complex heavy chain,Migration inhibitory factor-related protein 14,MRP-14,p14,S100 calcium-binding protein A9 |
| 2 | C, D, E, F (A, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence modifications
A, B: 1 - 114 (UniProt: P06702)
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | Cys 3 | engineered mutation |
| Phe 63 | Met 63 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26527.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 26688.2 |
