7UI3
Apo-form of Human Tryptophan 2,3-Dioxygenase Induced by NADH Binding
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tryptophan 2,3-dioxygenase | polymer | 380 | 45182.5 | 4 | UniProt (P48775) Pfam (PF03301) | Homo sapiens (human) | TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TRPO, Tryptophan pyrrolase, Tryptophanase |
| 2 | E, F, G, H (A, B, C, D) | alpha-methyl-L-tryptophan | non-polymer | 218.3 | 4 | Chemie (ZIQ) |
Sequence modifications
A, B, C, D: 18 - 389 (UniProt: P48775)
| PDB | External Database | Details |
|---|---|---|
| Met 17 | - | initiating methionine |
| Glu 390 | - | expression tag |
| His 391 | - | expression tag |
| His 392 | - | expression tag |
| His 393 | - | expression tag |
| His 394 | - | expression tag |
| His 395 | - | expression tag |
| His 396 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 180730.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 873.0 | |
| All* | Total formula weight | 181603.1 |
