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Crystal Structure of enolase family protein from Naegleria fowleri with bound 2-phosphoglyceric acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Phosphopyruvate hydratase	polymer	477	52357.0	2	UniProt (A0A6A5BXC3) Pfam (PF03952) Pfam (PF00113)	Naegleria fowleri
2	C, L (A, B)	2-PHOSPHOGLYCERIC ACID	non-polymer		186.1	2	Chemie (2PG)
3	D, E, F, M, O... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
4	G, H, K, N (A, B)	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
5	I, J, Q, R (A, B)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
6	S, T (A, B)	water	water		18.0	640	Chemie (HOH)

Sequence modifications

A, B: 44 - 555 (UniProt: A0A6A5BXC3)

PDB	External Database	Details
Met 36	-	initiating methionine
Ala 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag
His 40	-	expression tag
His 41	-	expression tag
His 42	-	expression tag
His 43	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	104713.9
Non-Polymers*	Number of molecules	16
	Total formula weight	1072.7
All*	Total formula weight	105786.6

*Water molecules are not included.