7UGB

Crystal structure of rat ERK2 complexed with docking peptide from ISG20

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Mitogen-activated protein kinase 1	polymer	380	43720.2	1	UniProt (P63086) Pfam (PF00069) In PDB	Rattus norvegicus (Norway rat)	MAP kinase 1,MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAP kinase 2,MAPK 2
2	I	Interferon-stimulated gene 20 kDa protein	polymer	15	1609.9	1	UniProt (Q96AZ6) In PDB	Homo sapiens	Estrogen-regulated transcript 45 protein,Promyelocytic leukemia nuclear body-associated protein ISG20
3	A	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)
4		water	water		18.0	146	Chemie (HOH)

Sequence modifications

A: 5 - 360 (UniProt: P63086)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Met 1	-	expression tag
Ala 2	-	expression tag
Ser 3	-	expression tag
Met 4	-	expression tag

I: 168 - 181 (UniProt: Q96AZ6)

PDB	External Database	Details
Ace 167	-	acetylation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45330.1
Non-Polymers*	Number of molecules	1
	Total formula weight	506.2
All*	Total formula weight	45836.3

*Water molecules are not included.